This profile evaluates the important oestrogen metabolites (2/4/16a-hydroxyestrones) as well as their methylated by products, which provides valuable information about oestrogen-related diseases, such as breast cancer, prostate disease risk, osteoporosis and certain autoimmune conditions. Oestrogen methylation is a critical step in the protective mechanism of oestrogen metabolism: methylation is required for the protective effects of 2-hydroxy-estrone, and for the safe detoxification of 4-hydroxy-estrone.
END20 Oestrogen Metabolism Plus FMV/24Hr (Genova Diagnostics)
Specimen Type: Urine
AVERAGE TURNAROUND TIME: 23 days
Patient Requirements: Please refer to full instructions sent with the kit.
2 hydroxy:16 alpha-hydroxyoestrone Ratio
2 – Hydroxyoestrone
2 – Methoxyoestrone
4 – Hydroxyoestrone
4 – Methoxyoestrone
4 – Hydroxyoestrone/4 – Methoxyoestrone Ratio